| PROFESSOR | INTERESTS |
|---|---|
| Martin D. Burke | Synthesis and study of small molecules with protein-like functions; molecular prosthetics; synthesis of complex natural products; iterative cross-coupling; MIDA boronates |
| Jefferson Chan | Synthesis of activity-based sensing probes for point-of-care diagnostic applications; development of chemically responsive platforms for on-demand and site-selective drug delivery; rationale design of therapeutic agents for neurological disorders and cancer |
| Scott E. Denmark | The invention, development, and application of catalytic asymmetric organic reactions; elucidation of structure-reactivity-selectivity relationships employing spectroscopic, crystallographic, and computational methods |
| Paul J. Hergenrother | Using compounds derived from synthetic organic chemistry and natural products to explore biological systems; examples include the synthesis and evaluation of anticancer and antibacterial agents with novel modes of action |
| Angad P. Mehta | Synthetic and molecular engineering platforms to: (i) recapitulate eukaryotic cell evolution, particularly, organelle evolution, (ii) develop synthetic tools for genome editing and (iii) develop vaccine candidates by constructing synthetic biochemical pathways |
| Douglas A. Mitchell | Reactivity-based natural product discovery; complex molecule structural elucidation and derivatization; structure-activity relationships and mode of action determination of biomedically important compounds |
| David Sarlah | Synthesis of complex natural products and the related chemical biology; methodology development; asymmetric catalysis |
| Scott K. Silverman | DNA as a catalyst |
| Wilfred A. van der Donk | Use of synthetic organic chemistry to address biological problems; antibiotic synthesis is of particular interest |
| M. Christina White | Reaction and catalyst discovery; site-selective Fe, Mn, and Pd catalysts for introducing oxygen, nitrogen, and carbon into C-H bonds for streamlining synthesis and late-stage functionalization of complex natural products and pharmaceuticals |
Other Faculty with Interests in Organic Chemistry:
| PROFESSOR | INTERESTS |
|---|---|
| Gregory S. Girolami | Organometallic chemistry; catalysis |
| Mary L. Kraft (faculty affiliate) | Biomembrane surface science |
| Liviu M. Mirica | Transition metal-catalyzed oxidative organic transformations |
| Jeffrey S. Moore (research faculty) | Self-healing polymers; mechanochemistry; nanostructures |
| Ralph G. Nuzzo (research faculty) | Functional organic materials |
| Eric Oldfield | Antibiotics; anti-cancer drugs |
| Lisa Olshansky | Synthesis and application of switchable metal ion ligands |
| Huimin Zhao (faculty affiliate) | Natural product biosynthesis; synthetic biology |